So I've been doing this for awhile, either TUMS or Rolaids before or after I drink. I do it because I feel it neutralizes the acids in my stomach so I don't throw up or get sick as often. I really enjoy drinking but I tend to get sick before I get drunk. I also rarely get red, with or without the Pepcid stuff.
Anyways, last Saturday I took my dad's prescription strength Famotidone (sp) of 20mg and it had a really peculiar side-effect. Basically I downed some Sake, 2 mixed drinks, 3 beers, 1 martini, and 2 shots within 2 hours and I was only slightly tipsy. Normally, that combination in such a short period of time would make me completely wasted since I'm only about 97 lbs.
So, what I'm saying is that if you plan on getting trashed, skip the Pepcid or take a smaller amount.